Aditya Aditya Fauzi Samsuri

APPLICATION OF NAÏVE BAYES ALGORITHM USING FORWARD SELECTION FEATURES IN DIABETES

Biomedical

Diabetes merupakan salah satu penyakit kronis yang prevalensinya terus meningkat secara global, dan memerlukan diagnosis yang cepat dan aku...

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Muchammad Naseer, Nova Agustina, Harya Gusdevi, Niken Riyanti

Neural Dynamic Network for Brain Tumor Classification: An Attention-Based Feature Selection Approach

Biomedical

Magnetic Resonance Imaging (MRI) plays a vital role in the early detection of brain tumors. However, standard Convolutional Neural Network (CNN) model...

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Ana Kurniawati, Aniqoh Hana Haura

Comparative Analysis Of Convolutional Neural Network Models For Digital Image-Based Melanoma Classification

Biomedical

Melanoma is one of the most malignant forms of skin cancer, with an incidence rate of 7.9% in Indonesia. Traditional biopsy-based diagnosis, though cr...

Review:

This study addresses a critical challenge in public health: the early and non-invasive detection of melanoma, a highly aggressive form of skin cancer....

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Cassidy N. Hardin, Aislinn O’Kane, Sara Quinney

UGT2B10 Variant Effects on Dexmedetomidine Metabolism Using Nicotine Studies

Biomedical

Background:Dexmedetomidine is a procedural sedative primarily metabolized by the UDP-glucuronosyltransferase (UGT) 2B10. UGT2B10 also contributes to n...

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Isaias Colon, Angelique Wise, Jenifer Prosperi

Sensitization of APC knock-out cells to Doxorubicin in vitro using KU55933, an ATM inhibitor

Biomedical

Background and Hypothesis: Triple negative breast cancer (TNBC) has the lowest 5-year survival rate among breast cancer subtypes, with Adenomatous P...

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Anslyn Freije, Melissa Abt, Tinslee Dilday, Elizabeth Yeh

Validation of Rubicon's Autophagy Inhibition Function Through HUNK Phosphorylation

Biomedical

Background and Hypothesis: HER2+ breast cancer uses the human epidermal growth receptor 2 (HER2) protein to grow. As an aggressive form of breast canc...

Review:

This abstract presents a compelling hypothesis regarding the role of HUNK phosphorylation in regulating Rubicon's autophagy inhibition function, parti...

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Kyle Richardson, Anika Shimonty, Joshua Huot, Fabrizio Pin, Lynda F. Bonewald

Sex-Dependent Effects of Irisin on Bone in an Aged Mouse Model

Biomedical

Irisin is a recently discovered protein that has garnered increasing attention due to its potential impact on metabolic health and disease prevention....

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Lillian Hatton, Elliot Androphy, Anne Rietz

Spatial Transcriptomics Demonstrates Tissue-Specific Differential Gene Expression in a Mouse Model of Spinal Muscular Atrophy

Biomedical

Background: Spinal muscular atrophy (SMA) is an autosomal recessive disease resulting from insufficient survival motor neuron (SMN) protein that affli...

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Alyssa Walker, Emily Seiden, Piper Wilburn, Ed Greenfield

Long Term Effects of Transient Romidepsin Exposure on Osteosarcoma Sarcospheres

Biomedical

Background:Osteosarcoma, the most prevalent primary bone cancer, disproportionally affects adolescents and young adults. Despite aggressive chemothera...

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Alexandra Cranston, Abigail Hall, Anushri Umesh, Nathan J. Alves

Exploring the Impact of Plasmin Inhibitors on Clotting Characteristics as a Novel Therapeutic for Thromboembolic Events

Biomedical

Background:Thromboembolisms are common, life-threatening emergencies. Systemic hemorrhaging post-thrombolytic treatment is an adverse reaction, highli...

Review:

This study introduces a compelling and potentially safer approach to treating thromboembolic events by investigating the co-delivery of plasmin and it...

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