Category: Biomedical
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Elеna V. Kuzubova, Alexandra I. Radchenko, Andrey А. Manuylov, Ariana M. Korokina, Natalia V. Koroleva, Ivan A. Yakovlev, Arthur A. Isaev, Roman V. Deev, Mikhail V. Korokin
Assessment of physiological parameters in the application of a double adeno-associated virus 9 with a codon-optimized DYSF gene for limb girdle muscular dystrophy type R2
Biomedical

Introduction: Gene therapy for Myoshi myopathy is extremely relevant, as it may become the first pathogenetic treatment for dysferlinopathy. The aim o...

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This study presents an important investigation into a gene therapy approach for limb girdle muscular dystrophy type R2 (LGMD R2), a form of dysferlino...

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Ekaterina V. Melnikova, Marina A. Vodyakova, Nikita S. Pokrovsky, Vadim A. Merkulov
Orthogonal approach and critical quality attributes for gene and cell therapy products
Biomedical

Introduction: Gene and cell therapy (GCT) products are revolutionizing medicine because they are made up of unique biological components like genetic...

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This manuscript addresses a critically important and timely topic: the quality control of gene and cell therapy (GCT) products. Given the inherent com...

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Ivan S. Koklin, Petr R. Lebedev, Alim A. Kochkarov, Oleg S. Gudyrev, Vladimir V. Gureev, Aleksandr A. Dolzhikov, Eduard I. Taran, Mikhail V. Korokin
Regulation of 11β-hydroxysteroid dehydrogenase isoforms – novel drug targets for osteoporosis therapy
Biomedical

Introduction: Osteoporosis is an significant medical and social public health problem in an aging or elderly society, the issue of pharmacological cor...

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This review article proposes a compelling novel pharmacological strategy for the treatment of osteoporosis, a significant and growing public health co...

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Medine Sibel KARAĞAÇ, Hamid CEYLAN
Effects of Natural Polyphenols Against Skin Aging
Biomedical

Aging is a natural process in humans that causes changes in the immune response, increased frailty and malignancy, and reduced skin elasticity. The ev...

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This paper, titled "Effects of Natural Polyphenols Against Skin Aging," addresses a highly relevant and timely topic given the global demographic shif...

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M. T. Acar
Effect of potassium fluoride on the structure and corrosion properties of anodic coatings on Ti6Al4V alloy
Biomedical

In this study, KF film was obtained by anodization method on Ti6Al4V material, which is preferred to be used in many areas such as the defense industr...

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This abstract presents a timely investigation into enhancing the surface properties of Ti6Al4V, a critically important alloy widely utilized in defens...

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Şengül DOĞAN, Burak TAŞCI, Türker TUNCER
Detection of acute lymphocytic leukemia (ALL) with a pre-trained deep learning model
Biomedical

Acute Lymphocytic Leukemia (ALL) is a type of cancer caused by immature lymphocytes in the bone marrow. Acute Leukemia is common in both children and...

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This paper presents an intriguing approach for the automated detection and classification of Acute Lymphocytic Leukemia (ALL) using peripheral smear i...

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Derya Okuyan
Kolon Kanserinde EGF Sitokininin İnsan Karbonik Anhidraz III (CAIII) Geninin mRNA Ekspresyon Seviyesine Etkisi
Biomedical

Karbonik anhidraz enzim ailesinin üyeleri karbondioksitin bikarbonat iyonuna geri dönüşümlü hidratasyonunu katalizleyerek dokulardaki CO2 taşınımını,...

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This study investigates the impact of EGF cytokine on the mRNA expression levels of human Carbonic Anhydrase III (CAIII) in the HT-29 colon cancer cel...

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Ratih Rinendyaputri, Holy Arif Wibowo
Ekspresi gen Bax pada kultur in vitro Inner Cell Mass (ICM) mencit
Biomedical

Inner Cell Mass (ICM) merupakan sumber sel punca embrionik (ESC, embryonic stem cell). Inner Cell Mass dapat diisolasi dari embrio tahap blastosis yan...

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This study investigates the efficacy of vitrification as a cryopreservation method for mouse Inner Cell Mass (ICM), a critical source of embryonic ste...

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Syaiful Rizal
Review: Mengenal metode sample pooling untuk pemeriksaan spesimen SARS-CoV-2
Biomedical

Pandemi COVID-19 yang disebabkan oleh SARS-CoV-2 telah mengakibatkan kerugian hingga kematian di berbagai negara. Peningkatan metode tes untuk skrinin...

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Ulasan ini membahas metode *sample pooling* sebagai strategi krusial dalam menghadapi tantangan skrining COVID-19, terutama di tengah pandemi SARS-CoV...

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Sugireng Sugireng, Rosdarni Rosdarni
Deteksi gen nuc isolat bakteri Staphylococcus aureus dari pasien ulkus diabetikum dengan metode PCR
Biomedical

Bakteri Stapylococcus aureus adalah salah satu bakteri yang dapat menyebabkan infeksi pada berbagai jaringan tubuh pada penderita ulkus diabetikum. Me...

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The study "Deteksi gen nuc isolat bakteri Staphylococcus aureus dari pasien ulkus diabetikum dengan metode PCR" addresses a critical issue in clinical...

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