Nur Ani, Riati Yulia Emanuel Awusi, Nur Anisa

Pemanfaatan Ekstrak Etanol Daun Binahong (Anredera cordifolia (Ten.) Steenis) sebagai Antioksidan Alami dalam Formulasi Krim Anti Aging

Introduction

Pemanfaatan ekstrak etanol daun binahong (anredera cordifolia (ten.) steenis) sebagai antioksidan alami dalam formulasi krim anti aging. Pelajari pemanfaatan ekstrak etanol daun Binahong (Anredera cordifolia) sebagai antioksidan alami dalam formulasi krim anti-aging. Penelitian menemukan formula III paling stabil.

Abstract

Another name for binahong leaves is Anredera cordifolia (Ten) Steenis) include tannins, phenolics, alkaloids, flavonoids, and saponins as secondary metabolites. Additionally, the flavonoid components in the leaves give them a strong antioxidant capacity. The purpose of this study is to ascertain whether or whether the cream dosage form of binahong leaf ethanol extract is stable, as well as the concentration at which the dose is most stable. The cold extraction method maceration and preparation evaluation is the technique employed. Based on the research findings, formulations 0, I, II, and III exhibit stability in cream dosage form and good homogeneity with an average spreadability of > 5 cm, adhesion that satisfies standards of > 1 second, and pH at the proper number 6 with skin pH. Based on the research findings, it can be said that all of the preparations FI, FII, and FIII as well as F0 as a negative control are stable in cream dosage form. Formula III, which satisfies all test evaluation standards and requirements for cream preparations, has the most stable concentration. Keywords: Red Binahong Leaves, Antioxidants, Ethanol Extract, Cream Abstrak Daun Binahong dengan nama lain (Anredera cordifolia (Ten) Steenis) mengandung metabolit sekunder yaitu alkaloid, flavonoid, saponin, fenolik dan tanin. Serta daun yang memiliki kandungan antioksidan tinggi dari senyawa flavonoidnya. Penelitian ini bertujuan untuk mengetahui stabil atau tidaknya ekstrak etanol daun binahong dalam bentuk sediaan krim dan pada konsentrasi berapa sediaan paling stabil. Metode yang digunakan yaitu metode ekstraksi dingin yaitu maserasi dan evaluasi sediaan. Hasil penelitian menunjukkan formula 0, I, II dan III stabil dalam bentuk sediaan krim dan memiliki tingkat homogenitas yang baik dengan daya sebar yang menunjukkan rata-rata > 5cm, daya lekat yang memenuhi standar yaitu >1detik dan pH yang berada pada angka 6 yang sesuai dengan pH kulit. Dari hasil penelitian dapat disimpulkan bahwa semua sediaan FI, FII, dan FIII serta F0 sebagai control negatif stabil dalam bentuk sediaan krim dan formula dengan konsentrasi paling stabil adalah formula III yang memenuhi seluruh syarat dan standar evaluasi pengujian untuk sediaan krim. Kata Kunci: Daun Binahong Merah, Antioksidan, Ekstrak Etanol, Krim

Review

This study investigates the potential of Binahong (*Anredera cordifolia*) leaf ethanol extract as a natural antioxidant in an anti-aging cream formulation. The authors correctly identify the presence of various secondary metabolites, including flavonoids, which are known for their strong antioxidant capacity. The primary objective was to assess the physical stability of the cream formulation containing the Binahong extract and to determine the most stable concentration. This research addresses a relevant area in natural product development for cosmetics, aiming to utilize a readily available botanical source for its purported beneficial properties. The methodology employed involved the cold extraction method of maceration for obtaining the ethanol extract, followed by the preparation and evaluation of cream formulations. The abstract reports that all tested formulations (F0 as negative control, and FI, FII, FIII with varying concentrations) demonstrated good stability. Specific physical parameters evaluated included homogeneity, spreadability (averaging > 5 cm), adhesion (> 1 second), and a pH value of 6, which is well-suited for skin application. Crucially, the findings indicate that Formula III exhibited the most stable concentration, fulfilling all specified evaluation standards for cream preparations. While the study successfully demonstrates the physical stability of the Binahong leaf extract in a cream base, several critical points require further detail for a comprehensive assessment. The abstract lacks information on the specific concentrations of the extract used in formulations FI, FII, and FIII, which is essential for reproducibility and understanding the "most stable concentration." Furthermore, although the title and abstract mention antioxidant capacity, there is no indication of whether the *final cream formulations* were tested for their antioxidant activity or if any *in vitro* or *in vivo* anti-aging efficacy was investigated. Future research should aim to quantify the antioxidant activity of the cream and explore its biological effects to substantiate the anti-aging claim, thereby providing a more complete picture of the product's potential.

Full Text

Comments

You need to be logged in to post a comment.